SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. Keywords: Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination Epub 2022 Oct 17. I got the covid vaccine and I now have what looks like - Reddit Pityriasis Rosea as a Possible Complication of Vaccination Against COVID-19 No use, distribution or reproduction is permitted which does not comply with these terms. 7 Articles, This article is part of the Research Topic, Creative Commons Attribution License (CC BY), Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Clinical manifestations and histopathologic findings of reported patients with pityriasis-rosea like eruptions following COVID-19 vaccination. COVID-19 vaccine hesitancy is a critical problem that hinders Careers. 2020;96(1142):753758. Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, et al. Would you like email updates of new search results? FOIA Pityriasis rosea has been found to be a symptom of the virus itself not the vaccine In fact there is no evidence the vaccine gives pityriasis rosea but instead getting covid itself does instead. Suchonwanit P, Leerunyakul K, Kositkuljorn C. Cutaneous manifestations in COVID-19: Lessons learned from current evidence. UpToDate (2021) 60:11501. The site is secure. doi: 10.1002/iid3.804. A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. 2023 The Authors. government site. 2021;35(8):e489e491. Dermatol Reports. COVID19 MapJohns Hopkins Coronavirus Resource Center. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. Careers. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE. Wien Med Wochenschr. doi: 10.1016/j.jdcr.2018.04.002, 12. 10.1007/S11356-020-12070-7 Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. The .gov means its official. PMC This is called a herald patch and may be up to 4 inches (10 centimeters) across. Before Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. The condition is clinically featured by blisters on the skin of the legs, buttocks and arms. The site is secure. 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. Scleroderma or CREST syndrome is a chronic, auto immune disease which manifests as. J Am Acad Dermatol. The https:// ensures that you are connecting to the Learning points: official website and that any information you provide is encrypted J Eur Acad Dermatol Venereol. Authors Elina Khattab 1 , Eirini Christaki 2 , Constantinos Pitsios 1 Affiliations 1 Medical School, University of Cyprus, Nicosia, Cyprus. Unable to load your collection due to an error, Unable to load your delegates due to an error. The third type of rash, known as Covid fingers and toes (sometimes described as chilblains), is where red and purple bumps appear on the fingers or toes.. Pityriasis rosea (PR) is an acute exanthematous disease. The exanthem was self-limited in both patients over a period of a month. Dermatol Res Pract. FOIA official website and that any information you provide is encrypted Drago F, Ciccarese G, Javor S, Parodi A. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. The ones found in people with pityriasis rosea are human herpesviruses 6 and 7. Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Br J Dermatol. Epub 2021 Jun 28. COVID-19; Vaccination; pityriasis rosea. Herald patch in the right hypochondrium followed by typical oval-shaped secondary plaques, Pityriasis rosea lesions on the upper extremities, MeSH Before government site. Comment on a case of pityriasis rosea shortly after Moderna COVID-19 Federal government websites often end in .gov or .mil. 15 Pityriasis rosea and COVID19 S. Veraldi, C. Spigariolo Medicine Journal of medical virology 2020 Then you may get smaller spots that sweep out from the middle of the body in a shape that looks like drooping pine-tree branches. Cite this: Skin Reactions After COVID-19 Vaccination . The .gov means its official. Int J Dermatol. Efficacy and safety of COVID19 vaccines: a systematic review. The .gov means its official. Secukinumab for pityriasis rubra pilaris (December 2022) SKIN CANCER. Abdullah L, Hasbani D, Kurban M, Abbas O. Pityriasis rosea after mRNA COVID-19 vaccination, Two cases of pityriasis rosea after the injection of coronavirus disease 2019 vaccine, Erythema nodosum, zoster duplex and pityriasis rosea as possible cutaneous adverse effects of Oxford-AstraZeneca COVID-19 vaccine: report of three cases from India, Atypical pityriasis rosea associated with mRNA COVID- 19 vaccine, Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male, Pityriasis rosea-like cutaneous eruption as a possible dermatological manifestation after Oxford-AstraZeneca vaccine: case report and brief literature review. The experience on a case of Pityriasis Rosea diagnosed after Covid 19 infection with atypical clinical presentation and low responsiveness to conventional treatments is shared. Pityriasis rosea developing after COVID-19 vaccination. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Keywords: HHS Vulnerability Disclosure, Help PDF Cutaneous reactions after CoronaVac and BioNTech vaccines In an American study, the average latency time was 13 days.7 In the previous cited Turkish-Egyptian study, the average latency time was 12.7 days.17 In 22 cases the eruption appeared 1-21 days after the second dose (average: 8.8 days); in 2 cases the eruption occurred both after the first and the second dose. doi: 10.1111/dth.15602. -. Veraldi S, Boneschi V, Cusini M, Maronese CA. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. It is possible that a relationship anti- Sars-CoV-2 vaccinationPR/PRLE exists; however, it is very rare, in consideration of millions of vaccinated subjects and the low number of reported cases with PR/PRLE. Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. Pityriasis rosea is a common viral infection that usually affects individuals between 10-35 years of age. Pearls and pitfalls: Adverse cutaneous reactions after COVID-19 vaccination. Bethesda, MD 20894, Web Policies Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. -. The vaccination campaign has been the most important strategy to combat the COVID-19 pandemic. Pityriasis rosea after Moderna mRNA-1273 vaccine: A case series. Unlike in our patient, oropharyngeal lesions were observed in approximately 16% of patients with typical PR (10). Data were independently extracted and accessed for bias. Department of Pathophysiology and Transplantation, Universit degli Studi, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy. Keywords: Martora F, Picone V, Battista T, Fabbrocini G, Marasca C. Dermatol Ther. Petechial Skin Rash Associated With Severe Acute Respiratory - JAMA Since you said you felt ill at the time getting the vaccine you had covid at the time. Manifestation of pityriasis rosea and pityriasis rosea-like eruptions Busto-Leis JM, Servera-Negre G, Mayor-Ibarguren A, et al.. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance, Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report, Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. In 4 patients PR appeared after the first vaccination; in one patient after the second one. Epub 2022 Mar 8. J Med Virol 2021; 93: 1850-1851. N Engl J Med 2020; 383:260315. No HHV-6 and HHV-7 reactivation is detected. Allergy Asthma Proc. Umakanthan S, Sahu P, Ranade AV, et al. Disclaimer. Erythematous-squamous, annular plaque on the presternal region. Federal government websites often end in .gov or .mil. Careers. Unable to load your collection due to an error, Unable to load your delegates due to an error. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Before This table includes information on vaccines that have published phase 3 trial data in the peer reviewed literature and are provisionally approved by the Australian Government Therapeutic Goods Administration (TGA). This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (, Anti-SARS-CoV-2, AZD1222, BNT162b2, mRNA-1273, Pityriasis rosea, Pityriasis rosea-like eruption. Bookshelf Disclaimer. J Invest Dermatol. Unable to load your collection due to an error, Unable to load your delegates due to an error. Federal government websites often end in .gov or .mil. Once a person has pityriasis rosea, it rarely recurs. Unauthorized use of these marks is strictly prohibited. In all patients laboratory examinations were within normal ranges. PRISMA, preferred reporting items for systematic reviews and metaanalysis. Here, we described a case of PR-like eruption that developed 14 days after Oxford/AstraZeneca vaccination in a 52-year-old Thai woman with glioblastoma. However, some hypotheses may be advanced: PR/PRLE following anti-Sars-CoV-2 vaccination may be just a coincidence; anti-Sars-CoV-2 vaccines cause a reactivation of HHV-6 and/or HHV-7; vaccines can induce a delayed hypersensitivity response clinically similar to drug-induced PRLE. Khan I, Elsanousi AA, Shareef AM, Tebha SS, Arif A, Gul S. Immun Inflamm Dis. But once it's gone, it doesn't come back. Federal government websites often end in .gov or .mil. Reactions related to the hair have so far not been reported. See this image and copyright information in PMC. 1. The https:// ensures that you are connecting to the As the worldwide vaccination campaign against the COVID19 pandemic continues, we emphasize that pityriasis rosea can result from new CoronaVac COVID19 vaccine, for both physicians and patients, and lesions may be reactivated after the second vaccination. PR is a common self-limited papulosquamous eruption typically presenting with a large solitary pink-colored patch or plaque (i.e., herald patch), followed by secondary eruptions of smaller erythematous patches or plaques with associated peripheral collarette scaling distributed along the cleavage lines of the trunk, forming a Christmas tree pattern (5). Some studies have identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins on endothelial cells and lymphocytes from PR-like lesions, consistent with direct viral invasion (3, 4). The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). We present a case of a pityriasis rosea-like rash occurring after Pfizer COVID-19 vaccination and review cases of pityriasis rosea (PR)/PR-like eruption (PR-LE) after mRNA COVID-19 vaccine published in the medical literature. official website and that any information you provide is encrypted doi: 10.1111/jdv.17316, PubMed Abstract | CrossRef Full Text | Google Scholar, 2. This site needs JavaScript to work properly. The clinics of HHV-6 infection in COVID-19 pandemic: pityriasis rosea and Kawasaki disease. If so, the reason may be simple: in several countries, BNT162b2 is the most used vaccine; iii) in 55 cases the rash was classified as PR, in 6 cases as PRLE; iv) in 39 cases the eruption appeared 1-12 days after the first dose (around: 4.8 days). All patients are currently in good general health. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. PMC Bathe or shower in lukewarm water. Accessibility We observed J Eur Acad Dermatol Venereol. KL drafted the original manuscript. Additionally, differences in incidence of this reaction after Pfizer and Moderna vaccination may suggest a differing host immune response incited by these vaccines which warrants further investigation. A Case of Purpura Annularis Telangiectodes of Majocchi after Anti-SARS Conflict of interest: The authors declare no potential conflict of interest. -, Johansen M, Chisolm SS, Aspey LD, Brahmbhatt M. Pityriasis rosea in otherwise asymptomatic confirmed COVID-19-positive patients: a report of 2 cases. Please enable it to take advantage of the complete set of features! Pityriasis is linked mainly with herpesviruses 6 and 7; only a small number of cases have been reported in association with vaccinations (e.g., yellow fever, influenza, hepatitis B, human. Pityriasis rosea and pityriasis rosea-like eruptions: how to distinguish them? Environ Sci Pollut Res. Dermatol Reports. HHS Vulnerability Disclosure, Help Unable to load your collection due to an error, Unable to load your delegates due to an error. An official website of the United States government. what happened to freddy carlson from kindig it design Your Random Rash Could Be Pityriasis Rosea | Allure Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. government site. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A Four patients were subjected to the second vaccination, but no skin lesions appeared. Clipboard, Search History, and several other advanced features are temporarily unavailable. Laboratory investigation results (i.e., complete blood count, blood chemistry, C-reactive protein level, erythrocyte sedimentation rate, serological test for syphilis, plasma polymerase chain reaction (PCR) for human herpesvirus (HHV)-6 and HHV-7, and reverse transcription-PCR for COVID-19) were unremarkable. Pityriasis Rosea as a Possible Complication of Vaccination Against COVID-19 2023 Apr;11(4):e804. 2023 Mar 3;14(2):207-212. doi: 10.4103/idoj.idoj_449_22. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. walker hayes daughter. doi: 10.1111/jdv.12942, 13. SV, CAM, MC, VB, collected the data. In a registry-based study, PR-like eruption was observed in only 12% of patients (14). Pityriasis rosea as a cutaneous manifestation of COVID19 infection Pityriasis rosea developing after COVID19 vaccination. Epub 2021 Aug 7. Numerous scattered erythematous plaques with fine scale oriented along skin cleavage, Herald patch of pityriasis rosea. doi: 10.1111/jdv.17342. Involvement of the oral mucosa has also been reported in as many as 50% of all cases (11). Numerous scattered erythematous plaques with fine scale oriented along skin cleavage lines, most appreciable on the upper portion of the chest. Pityriasis rosea is a common rash that usually begins as a round or oval-shaped patch and spreads in stages in a characteristic pattern. Pityriasis rosea and pityriasis rosea-like eruption after anti-SARS-CoV-2 vaccination: a report of five cases and review of the literature. (2015) 2015:253154. doi: 10.1155/2015/253154, 14. Pityriasis is linked mainly with herpesviruses 6 and 7; only a . 2005;124(6):12341240. Clipboard, Search History, and several other advanced features are temporarily unavailable. PRISMA, preferred reporting. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases. Pityriasis Rosea: Diagnosis and Treatment | AAFP Unauthorized use of these marks is strictly prohibited. government site. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature JAAD Int. CONCLUSION: The association between pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccines was established, but given the scarcity of studies, there is a need to conduct different clinical trials to confirm this association further and study the etiology and mechanism of the disease. A 3-cm oval plaque with peripheral scale, larger than the other lesions, was present on the inferior portion of the right breast. Please enable it to take advantage of the complete set of features! Hum Vaccin Immunother. The .gov means its official. MeSH official website and that any information you provide is encrypted Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. It is possible that a relationship between anti- Sars-CoV-2 vaccination and PR/PRLE exists; however, it is very rare, in consideration of millions of vaccinated subjects and the low number of reported cases of PR/PRLE. 8600 Rockville Pike 2022 Nov-Dec;67(6):802-804. doi: 10.4103/ijd.ijd_562_22. Suchonwanit P, Triamchaisri S, Wittayakornrerk S, Rattanakaemakorn P. Leprosy Reaction in Thai Population: A 20-Year Retrospective Study. JAAD Case Rep. 2021;7:9394. Although the exact pathophysiologic mechanisms of PR after vaccination remain unclear, immune responses to COVID-19 vaccines and disruption of T-cell mediated control of latent infections were implicated (12, 1518). SARS-CoV-2 disease, COVID-19 infection, is a multi-system illness that has afflicted people all over the world. Bookshelf Some patients may have a cold before the rash. The first sign of pityriasis rosea is often one large patch on the skin, which is followed smaller patches or bumps. National Library of Medicine Manifestation of pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccine: A systematic review. Although it is known that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be associated with skin manifestations, a limited number of images are available in the literature at this time. Results: SPSS statistical software version 25 was used for appropriate inferential statistics. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. and transmitted securely. . Gianotti-Crosti Syndrome is a rare skin disease affecting children at the first years of age. Would you like email updates of new search results? Background: Although histopathologic characteristics of PR are also observed in PR-like lesions, the presence of dyskeratotic keratinocytes, interface dermatitis, and eosinophilic infiltration in the dermis may be more prominent in PR-like eruptions (11). Cazzato G, Ambrogio F, Foti C, Capuzzolo M, Trilli I, Casatta N, Lupo C, Carrieri M, Daini D, Colagrande A, Maiorano E, Ingravallo G. Diagnostics (Basel). Pityriasis rosea - Symptoms and causes - Mayo Clinic 8600 Rockville Pike Drago F, Ciccarese G, Javor S, et al. In addition to reactivation of HHV-6 or HHV-7, PR can be triggered by some drugs (like angiotensin-converting enzyme inhibitors alone or in combination with hydrochlorothiazide, sartans plus hydrochlorothiazide, allopurinol, nimesulide, and acetyl salicylic acid (2) and vaccines (such as smallpox, poliomyelitis, influenza, human papillomavirus, diphtheria, tuberculosis, hepatitis B, pneumococcus, and yellow fever vaccines) (3). It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. Pregnant women are in a high-risk group for serious complications from pityriasis rosea. -. Human herpesviruses 6 and 7 are common. government site. The pathogenesis of this relationship is unknown. Future studies should investigate oral lesions in SARS-CoV-2-positive subjects and after COVID-19 vaccination in the pediatric population, taking into account viral variants and newly developed vaccines. Epub 2021 Apr 26. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. government site. Clipboard, Search History, and several other advanced features are temporarily unavailable. Ciccarese G, Parodi A, Drago F. SARS-CoV-2 as possible inducer of viral reactivations. Vaccination is one of the cornerstones in the efforts towards ending the coronavirus disease 2019 (COVID-19) pandemic. Epub 2022 Jan 5. As our patient did not receive a COVID-19 vaccine, we cannot evaluate the latter based on the present case. PRISMA flowchart. Pityriasis Rosea | Cedars-Sinai doi: 10.1111/bjd.20143. Due to the temporal relationship between vaccination and onset of rash, COVID-19 vaccination was the most likely etiology. It then causes many more small patches. Figure 3. Factors affecting the severity of central centrifugal cicatricial alopecia. doi: 10.1016/j.jaad.2020.04.094, 8. Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in But some patients also are developing delayed skin reactions on. See this image and copyright information in PMC. (2021) 35:e5468. Careers. Federal government websites often end in .gov or .mil. SARS-CoV-2 vaccine; cutaneous side-effects; infection; papulosquamous; skin diseases; vaccine hesitancy. Accessed February 2, 2022. A number of vaccines have been produced to combat the current COVID-19 pandemic, and a variety of side effects have been recorded following the vaccination. (2021). Pityriasis rosea (PR), PR-like eruptions (PR-LE), and herpes zoster have been frequently reported during the COVID-19 pandemic and following COVID-19 vaccination. Literature data about PR/PRLE after anti-SARS-CoV-2 vaccination may be summarized as follows: i) the infection occurs both in males and females (in several articles the gender was not reported); ii) the age ranges from 19 to 82 years (the count of the mean age is impossible because in several articles patients age was not specified). 2021 Sep;60(9):1150-1151. doi: 10.1111/ijd.15700. 2022 Jul 6;15(1):9503. doi: 10.4081/dr.2022.9503. -. Vaccine-Related Eruptions of Papules and Plaques Following COVID-19 Vaccination - A Case Series. Pityriasis rosea: Who gets and causes - American Academy of Dermatology The .gov means its official. Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. Please enable it to take advantage of the complete set of features! The patient developed papulovesicular lesions in the crease lines of the trunk and extremities, four days after inoculation with a recombinant coronavirus vaccine (Covishield, India). Epub 2022 Jun 13. 2020;33:E13730. Bethesda, MD 20894, Web Policies Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine, Cutaneous adverse reactions after m- RNA COVID-19 vaccine: early reports from Northeast Italy. Pityriasis rosea - NHS Oral baricitinib for moderate to severe alopecia areata in adolescents . Researchers Continue to Find Clues About MIS-C - Yale Medicine doi: 10.1159/000517971. PS conceptualized the case report and revised the manuscript. They described a patient developing pityriasis rosea (PR) 2 hours after the second dose of Moderna COVID-19 vaccination. The rash can be itchy. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. Explore the world of Jaguar cars and learn more about models When You Just Know - The Skin Cancer Foundation World J Clin Cases. 2022 May;35(5):e15391. J Am Acad Dermatol. . government site. Atypical pityriasis rosea associated with mRNA COVID-19 vaccine National Library of Medicine doi: 10.1016/j.jaad.2021.03.092, 15. 2021 Nov;34(6):e15129. (2021) 85:4655. Covid: Skin rashes are ONLY symptom for 21% patients, says KCL study The four stages of pityriasis rosea are: Preliminary stage: You feel ill for a day or two. Clipboard, Search History, and several other advanced features are temporarily unavailable. Conclusion: Skin Diseases Associated With COVID-19: A Narrative Review PMC 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. National Library of Medicine Psoriasis and COVID-19 Vaccine Boosters | Everyday Health It's easily mistaken for scalp psoriasis and vice versa. Veraldi S, Boneschi V, Cusini M, Maronese CA. Reply to "the significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations" by Ciccarese G. et al. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case J Eur Acad Dermatol Venereol. sharing sensitive information, make sure youre on a federal sharing sensitive information, make sure youre on a federal 2023 Apr;11(4):e804. Here, we report the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. Only some cases of PR/pityriasis rosealike eruption (PRLE) after anti-SARS-CoV- 2 vaccination have been reported.1-18 In the period May 2021-February 2022 we observed five cases of clinically typical PR that appeared after anti-SARS-CoV-2 vaccination with BNT162b2 (3 patients) or mRNA-1273 (2 patients). The significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations. Epub 2021 May 10. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. Catal A, Muoz-Santos C, Galvn- Casas C, et al.. Cutaneous reactions after SARS-COV-2 vaccination: a crosssectional Spanish nationwide study of 405 cases, Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. (2020) 83:e5760. eCollection 2022. Patient n. 1. Background: After introducing Covid-19 vaccines, a few side effects were reported, pityriasis rosea being one of them.Therefore, this study will systematically review its manifestation afteradministration.Methods: Databases were searched, covering a timeline from December 1, 2019 to February 28, 2022.Data were independently extracted and accessed for bias. 2022;S0738-081X(22)00002-5. Manifestation of pityriasis rosea and pityriasis rosea-like - PubMed