Foam Booster/Stabilizer; Rheology Modifier; Stabilizer-Emulsion; Suspending Agent . Hi, let us know if you have any questions as you visit our website. Fiber supplements can lessen the absorption of some . Avicel PH-200 microcrystalline cellulose NF, Ph. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. Product Name: Microcrystalline Cellulose E460 1.2. PDF Material Safety Data Sheet - FMC Report Category. Molecular weight: Not Applicable 1.5. MSDS Ref. Co-processed excipients deliver functional synergies to address formulation challenges with simplified, single ingredient solutions. FIRST AID MEASURES Eye Contact Hold eyes open and rinse slowly and gently with water for 15 to 20 minutes. Copyright 2023 by International Flavors & Fragrances Inc. IFF is a Registered Trademark. Manufactured by: China . Formulators select it when they need to enhance a formulations robustness especially when less compactable diluents and binders are used. MATERIAL SAFETY DATA SHEET Version: 1.0 1. /Resources 2 0 R Microcrystalline Cellulose. Further elaborations can then be performed on the obtained material to produce many other grades of Microcrystalline cellulose. 1. % 1.3. Alubra sodium stearyl fumarate from IFF Pharma Solutions is a comparatively hydrophilic lubricant widely used in capsule and tablet formulations. Avicel co-processed grades are co-spray dried blends of Avicel microcrystalline cellulose with synergistic pharmaceutical excipients to yield functional benefits beyond simple physical blends. FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . Microcrystalline Cellulose Side Effects. ( on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. Micro Crystalline Cellulose - Accent Microcell Pvt. Ltd. The formed cellulose molecules pack themselves closely to each other, stabilised through hydrogen bonds, creating crystalline regions interspersed with amorphous regions. Burger King, McDonald's and other fast food companies list in the ingredients of several of their foods, microcrystalline cellulose (MCC . MATERIAL SAFETY DATA SHEET - Sevron It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. Similarly, the European Food Safety Agency has also evaluated Microcrystalline cellulose and established that it is not absorbed systemically and excreted unchanged. (AEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEM %)piQpFNnFu\4m4( ESE;m& %QL((((((((((((((((((((((((((((((((((((((((P3NhC Microcrystalline cellulose (cas 9004-34-6) SDS(Safety Data Sheet) /MSDS 130. cas:9032-51-3 msds CELLULOSE PAB. Kristensen, T. Schfer, P. Kleinebudde, Direct pelletization in a rotary processor controlled by torque measurements. ?t#_n|z%4n#(!:lMD~{mfvv}Na0vx?? Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named mechanically disintegrated D.P cellulose. Aquacoat ECD is an aqueous dispersion of ethylcellulose used for sustained release barrier or slow release pharmaceutical coating, moisture barrier and taste masking applications for tablet and multi-particulate dosage forms. Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. /Group << /S /Transparency /CS /DeviceRGB /I false /K false >> Microcrystalline Cellulose (MCC) Manufacturing | Pharmaceutical Grade Microcrystalline Cellulose - an overview | ScienceDirect Topics Pharmacel 112 can be used in a wide range of oral solid dosage (OSD) forms as binder, compressing agent . Comments: The human studies including the use of radiolabelled microcrystalline cellulose show complete absence of digestion or absorption. PROSOLV SMCC, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD).A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. The main source of cellulose is woody plants, since it is the main building block of the cell walls of higher plants. /Contents 4 0 R Explore how you can develop your career and bring your creative ideas to life at IFF. Note that Avicel Microcrystalline cellulose is available in different particle sizes and moisture grades that have different properties and applications. Within the pharmaceuticals field, where the bulk of this material is utilised, Avicel Microcrystalline cellulose functions as a filler and diluent, dry binder, flow, disintegrating, and compression aid in tablets, capsules, and granules. Microcrystalline Cellulose (MCC) Manufacturing Industry. Assay for carboxymethycellulose sodium, wt % 8.3 to 13.8 . JRS Pharma: PROSOLV SMCC 90: Microcrystalline Cellulose, Colloidal Silicon Dioxide: 125: 0.25 - 0.37: Formulas in which a balance of flow and compaction is required. It is also inert and biocompatible. endobj Avicel PH-101 - Cellulose, Cellulose powder PDF Safety Data Sheet - Parchem Avicel Microcrystalline cellulose is a type of cellulose, a naturally-occurring, large molecular weight polysaccharide found in woody plants. Learn about our new global sustainability platform, Learn about FMC's industry leading goal of net-zero emissions by 2035, Learn about FMC's differentiated biologically-based crop solutions. xv}O2' H~KEe9>G/,:9\i : 160182. CAS #: 9004-34-6 . << iQuLyI4D@yq#u0dZt=0?QUz{K6by_C"vW~Nj$bo? All Rights Reserved. The short-term limit for total inhalable dust is 20 mg/m3. Alginates also function as actives in some anti-reflux products. >z+{!A6wy @nLK3R#hRn sba3;b61V:#Z3X,*?RC!wPmqd7WkA'aZMt6PFV3SEvlY'=p.mn[I{puc\6'ZIyI%rD'zA!"t3I2F ^R;LK,?:&THv*y^K> o0Af?J9J-{s2&cCn)32ADzl%sS5O~J[ ( Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. Avicel Microcrystalline Cellulose: A Guide to Grades and Uses The highly reactive amorphous regions selectively hydrolyze, releasing the crystallites, which are subsequently mechanically dispersed. It is an excipient approved for use in pharmaceutical products and is also GRAS listed and accepted for use as a food additive in Europe and the United States and is included in the FDA Inactive Ingredients Database (oral: powders, suspensions, syrups, and tablets; topical & vaginal products). Unique functionality for a broad range of pharmaceutical applications. Alubra is also less susceptible to over-blending contributing to more flexible process conditions and reduced waste due to over blended batch failures. Dupont acquired the microcrystalline cellulose business of FMC Corporation in 2017. SUBSTANCE IDENTIFICATION 1.1. : 51395-75-6 Date Approved: 01/31/2008 Revision No. Have an order or account question? GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA 1. 1.5% w/w), especially designed for formulating active pharmaceutical ingredients (APIs) with a high sensitivity for moisture. 4. Characterisation of the interactive properties of microcrystalline X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. /Producer(Sub Systems, Inc.)/CreationDate(D:20181207095625+05'00')/ModDate(D:20181207095625+05'00')/Creator(Sub Systems, Inc.) 1.3. Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Magnesium stearate 557-04- 209-150-3 Not Listed * 0.25 - 0.37. Buy Chemicals. Delivering efficient and robust formulations. Avicel RC-591 & CL-611 - Description. Biologicals by FMC. Doses up to 30 g per day appear to be . Cellulose, microcrystalline | C14H26O11 | CID 14055602 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . XiDqLN MD'F2`jI7ZWu,JK%5e9~:R>LAm\WyY0lk=ZNP;pZ23)P0GG~%e[ d8GIXRo&. GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. CAS #: 9004-34-6 1.6. It . If breathing is difficult or if . G2W4de=u183KGH{ vQ#4:1\wc Revision No. Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. These grades have particle sizes ranging from <30 to approximately 200. Catalog Number 102331. SEM micrographs of microcrystalline cellulose (MCC) models with a scale bar of 100 m [1] . The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. CoA. The Microcrystalline Cellulose monograph will be incorporated into and become official with the Second Supplement to . They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. Its used in capsules and tablets, both in wet granulation and direct compression processes, where it serves as a moisture adsorbent, tablet, and capsule diluent, and tablet disintegrant.It is also widely used as a supplementary formulation aid, primarily to enhance the . SDS - Safety Data Sheet. The typical mean particle size is 20200 m. %PDF-1.5 Their nomenclature and recommended applications are shown below: Co-processed Avicel grades are high functionality materials designed to bring added performance over and above what standard grades offer. }[eD-1-8$#Yi^$o8Nc6vwfw;wBT~[Rgi1?%T*/J:/'+Gf'Ae*j@{Rh+2oN|Sbtt;z#v8})F#z=:*]q+U>+ .e ^Q-{@ RPC t/(If>8P&%wNPMJw,VI2aUqRqe3bC,a;C&4RQSf*(=I$r{'%jmk1LUZV(*is6r&wQPAAoID4p?,"lp:wE+)v(_w 'yelVnMh=gIYjK:9v{$G;b8=lGG1_,h^0F2`a~Kusz1p#NS*qt6,F:7+Rma-4u} DINFzJ"Mlctg*~HEge MATERIAL SAFETY DATA SHEET. Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. Synergies to simplify formulation challenges and reduce operational costs. Avicel RC 591 MSDS CasNo.51395-75-6 - lookchem.com If you have Crohn's disease or a history of bowel obstruction, discuss with a doctor or pharmacist about drug interactions with fiber supplements.. No. < gV2@o2s&WS@Et%Up:`U '_ h?8qyP=&> GFprm9A!uu1 }&*kQ c^&eX}^K}h9YCb2L(yL):,+g8_u. Have an order or account question, find answers in our Online Support articles. Page 1 of 8. stream Molecular weight: Not Applicable 1.5. TEXTURECEL is highly purified sodium carboxymethyl cellulose (NaCMC) that forms clear solutions in water at all temperatures, has exceptional water binding properties, and is available in a wide range of viscosity grades. 5 0 obj 2021 Annual Report. Instead, they obtained a stable colloidal suspension. <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 6 0 R/Group<>/Tabs/S>> Studies from the World Health Organisation and the European Food Safety Agency have concluded that Microcrystalline cellulose has no safety concerns for the public when used in animal nutrition. Revision No. Molecular Weight null. HAZARDS IDENTIFICATION EMERGENCY TELEPHONE NUMBERS (302) 451-0100 (FMC Plant - Newark, Delaware) (303) 595-9048 (Medical - U.S. - Call Collect) For leak, fire, spill, or accident emergencies, call: (800) 424-9300 (CHEMTREC - U.S.A. & Canada) (703) 527-3887 (CHEMTREC - Collect - All Other Countries) EMERGENCY OVERVIEW: Off-white, free-flowing, odorless powder. Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. Microcrystalline Cellulose (MCC) MSDS 1. Htn@sHaYoEJ*H[G&o)o9;0s N'3[*%M]vAu#9Tqpg9D& 8 0 obj Are you looking for information about products and services by region? Aquacoat sustained release coating is a pseudo latex aqueous dispersion of water insoluble polymers used for sustained and enteric coating applications. Validity Area. >> . Avicel PC 611 (FMC Biopolymer) | CosmeticsAndToiletries.com Learn about FMC's differentiated biologically-based crop solutions. MATERIAL SAFETY DATA SHEET. q9;v80q>jZ The global Microcrystalline Cellulose (Mcc) market size is projected to reach multi million by 2026, in comparison to 2022, at unexpected CAGR during 2022-2026. Patel, F. Podczeck, Investigation of the effect of type and source of Microcrystalline Cellulose on capsule filling, International Journal of Pharmaceutics, 128 (1996) 123-127. More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. SCMm_>x^O9l (n. zW0} kAmS AYiy QJVWwi ED`52u-I~_ViT3+3kIT D2/A5vP5MHt(*vCBZ5UALFS0Mr v6t3dDda!03O$V>S6n| 3Fz. q9;v80 The table below lists the typical nutritional information of microcrystalline cellulose: Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g)1. J]3yzZ2Z$mZ7o%-Xyq'()V9KX0gk~AA Cu:3(]N"AQdUt~h|P Microcrystalline cellulose 9004-34-6 <1 Synonyms are provided in Section 1. endobj Truly distinctive drug delivery solutions. However, consumption of large quantities of the material may have a laxative effect. Material Safety Data Sheet TALSTAR S INSECTICIDE Version 1 Page 1 / 8 SDS # : 6320-A This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS) requirements. Avicel CL-611 Microcrystalline Cellulose and - FMC - YUMPU Frijlink, Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) Microcrystalline Cellulose, European journal of Pharmaceutics and Biopharmaceutics, 59 (2005) 133-138. METHOCEL products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe. The product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. In Cellulose and Cellulose Derivatives in the Food Industry, T. Wstenberg (Ed. Gloves, eye protection and a dust mask should be used. Standard, 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS . No. 102331. 86dXeaAjHe%d*`&>>&_p}=X|_% fTtC aB s!YaxHWtGr"GQ 5S"fMS+_;x@@5 zjrK=;OA:il)b> e ei'wm~oh!=Z@Y:J0#8On`T./iC}^o%7KS"$ rf*Z;JTL-uOHH%%Z,029J_ ( endstream endobj 526 0 obj 465 endobj 527 0 obj << /Filter /FlateDecode /Length 526 0 R >> stream Quantity: 1 700 kgs. A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. More sophisticated drug discovery techniques have led to pipeline compounds that require solubility enhancement to be therapeutically effective. For this reason, nutritionists regard standard powdered microcrystalline cellulose as having zero energy content. l~5C Battista, O. pb7c8BHqCRX_eL +90w~ gk[YBkf9eDNJdNn q^16mi=4Sr0~{lZ>yvMqS'e,MqB?;Oy9s'$8asJgEh0SS>|J58ub^q c Dh)#t'kTfIZT1-_y"+wXj,qo!~ozc}ZemZ``$'vj{, Ga;]2iY*DIh~F3Z!.pkL:bHHBTbIcw9.Xo$4,?On4s=R,KLz /M|#PF(j%j oF2[5 ,rx)bd1$LM4Dc-d\@W D?A?L/7>s]-};Z if^+e3}AeQ# U%l3K?WW$iJ:tSS8M /&N2R3d2Nl2u]qg*WVkq2lhJZIiE++nKfq)sO~z(d| 7u4w!o}::#l}tEw'M}BEntaugq**t|KZUTe-1J+|. stream : 1. SUBSTANCE IDENTIFICATION 1.1. Avicel is a brand name by Dupont for grades of Microcrystalline cellulose. It is hygroscopic and insoluble in water. Microcrystalline cellulose: The inexhaustible treasure for The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. Wu, K. Zuurman, H.W. CAS 9004-34-6, pH 5 - 7.5. Go to Investor Relations. Avicel RC-591 & CL-611 | IMCD US EMCOCEL XLM 90. Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. endstream The wood pulp is depolymerized by acid hydrolysis and turned from a fibrous material to a white freely-flowing powder. EP1551879A4 - Production of microcrystalline cellulose - Google . Substance Information - ECHA - Europa We respect your privacy FMC Privacy Policy. The representative usage of Avicel PH-101 and Avicel PH-102 Microcrystalline cellulose in wet granulation and direct compression is shown in the following two examples. endobj Find answers in our support articles. Product name: Microcrystalline cellulose; CBnumber: CB4217972; CAS: 9004-34-6; EINECS Number: 232-674-9; Synonyms: MICROCRYSTALLINE CELLULOSE,cellulose; It should be noted that native cellulose itself is completely indigestible, and its hydrolysis during the production of microcrystalline cellulose does not alter its behaviour in the intestine. Synonyms: Cellulose, Cellulose powder, Cotton linters. <> Cellulose microcrystalline MSDS - 102331 - Merck Pharmacel 112 - Home - DFE Pharma Aqueous suspensions of microcrystalline cellulose have . Eur., JPE . All rights reserved. Heavy metals, % NMT 0.001 2 0 obj Microcrystalline Cellulose E460 MSDS 1. Global Microcrystalline Cellulose Market (MCC) Size Will Reach US$ 1360 Quick Links. vdZ@Rgl{eU+7N!3!|hUmW)~}U*7k i@j)q["MEydtP"ftFu]t }JN~A"8lz7#}J.i@ qaj/QU<5OrVMfl{pL? The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Product and Company Identification Product Name Microcrystalline Cellulose CAS Number 9004-34-6 Parchem - fine & specialty chemicals 415 Huguenot Street New Rochelle, NY 10801 (914) 654-6800 (914) 654-6899 parchem.com info@parchem.com EMERGENCY RESPONSE NUMBER AFFINISOL HPMC HME offers hot melt extrusion process flexibility in choosing a polymer viscosity that optimizes drug release profiles and against the factors affecting solubility. ;(Imu9Jv_ YhnHTbwP*:mg"T{BO;!QR e,cqO! Test Data Available. The table below shows the most common physicochemical parameters of this raw material. FMC has deep roots in the food production system worldwide learn more about our latest advances in the future of agriculture. Comprecel MCC (Microcrystalline Cellulose) is a pharmaceutical excipient derived from nature's most abundant and renewable raw material-wood pulp. Microcrystalline cellulose (Avicel, FMC Corporation) is prepared by acid hydrolysis of cellulose using 2 M hydrochloric acid at 105 C for 15 min. ES454445A1 - Procedimiento para preparar una crema lactica de buena con However, with many different grades (standard and specialty) on offer, how do you select the correct material for your needs? ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM Microcrystalline Cellulose Market Forcast 2023 To 2028 : In-depth Avicel PC 611 Microcrystalline Cellulose. Chemical Formula: (C6H10O5)n 1.4. Alginates from IFF are an excellent choice for consistent performance in a variety of applications. Manufacturer: FMC BioPolymer. Learn about FMC's industry leading goal of net-zero emissions by 2035. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose using a Waring Blender. PDF Nfpa 491 Hazardous Chemicals Data Avicel Microcrystalline cellulose also serves as a moisture adsorbent and as a general-purpose formulation improver. Production of Pharmaceutical Grade Microcrystalline Cellulose. Carrageenan is a naturally occurring family of hydrophilic polysaccharides extracted from several closely related species of red seaweeds. Terms and Conditions Compliance Solutions Industries About 3E News & Events . Place an order online, track your orders, download SDS and TDS, and see your quotes, all in one secure place. It does not interfere with other nutrients when added to food products, and is instead, an excellent carrier and stabiliser, helping prolong the viability of food products. When selected in wet granulation, the optimum level of use is between 5 and 20%, although higher levels have been successfully used. /Type/Page <> This extends the funcionality of microcrystalline cellulose to meet specific viscosity, gelling, suspension and stabilizing properties ChemPoint is an approved supplier of LATTICE MCC in industrial applications, providing dedicated marketing, sales, order fulfillment, and technical support for customers in the EMEA region, Protect and improve AI potency, entrap oil droplets and improve stability, physical barrier that helps suspend particles and breaks down under shear and reforms quickly under rest. : CL-611NF Date Approved: 01/13/2010. Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Manufacturer FMC Corporation Product code 103-B Revision date 2014 September 30 Language English. Since cellulose contains both amorphous and crystalline regions, when the crystalline regions are mechanically and chemically isolated and elaborated, various useful ingredients in the form of cellulose crystals are obtained, one of which is Avicel Microcrystalline cellulose. Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. PharmaCentral 2021 . /Parent 3 0 R PDF (2.77 mb) 2021 FMC Sustainability Report. Material safety data sheet - FMC Corporation. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. Cellulose, microcrystalline | C14H26O11 - PubChem Although the breakup of cellulose to form colloidal microcrystalline cellulose has no impact on calorific content of the material, colloidal microcrystalline cellulose contain soluble components (hydrocolloids) that are introduced during processing, which add calories to the product. Apply today! PDF MATERIAL SAFETY DATA SHEET - Stobec Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. stream Remove PDF (28.38 mb) 2022 Corporate Fact Sheet. Regulatory Information undefined. Your file is uploaded and ready to be published. Home | FMC Corp PDF MATERIAL SAFETY DATA SHEET Product Name: MICROCRYSTALLINE CELLULOSE As some of the data above show, microcrystalline cellulose possesses unique physicochemical properties that set it apart from native cellulose. Assay: 0.98 Appearance: Off white to slight yellow solid Package: 1L 5L 10L 25L bottle Storage: Stored in shaded, cool and dry places Transportation: Handle with cares to avoid damaging the packages. 4 0 obj Of all the different brands and grades of MCC, Avicel PH 101 or Emcocel 50 has been the most widely used. common form is used in vitamin supplements or tablets. Microcrystalline cellulose in certain fiber supplements may cause mild side effects ().These may include gas, bloating and increased stool production.. AVICEL RC 581. You have already flagged this document.Thank you, for helping us keep this platform clean.The editors will have a look at it as soon as possible. The fumarate moiety of Alubra increases its melting temperature, which allows for greater functionality at high press speeds while the stearate chain maintains the lubricity of the compound and supports low ejection forces. Avicel Microcrystalline cellulose occurs as a white, odourless, tasteless, fibrous powder composed of porous particles. There is a secret ingredient in your burgers: wood pulp - Quartz AFFINISOL hydroxypropyl methylcellulose (HPMC) is a water-soluble cellulosic polymer that can help optimize solubility enhancement of poorly soluble drugs by maintaining stable solid dispersions and inhibiting API crystallization. Chemical Name Microcrystalline cellulose (INCI Name): MCC, cellulose gel Common Name Avicel PH105 Microcrystalline Cellulose CAS Number 9004-34-6 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice No data available If Inhaled Remove person to fresh air. 9,LL!z In large quantities it provides dietary bulk and may lead to a laxative effect. Microcrystalline cellulose - Safety Data Sheet - ChemicalBook >> Product Specifications: Chemical and Physical: Loss on drying, % NMT 6.0* Viscosity, cps, 1.2% solids, 120 sec 39 to 91 . 4 0 obj <> Protect them from sunshine or rain. Microcrystalline Cellulose Market Size to Increase Significantly in It is available in different grades and particle sizes. Currently, it is marketed both directly and indirectly (through distributors) depending on the country in question. q86@on$^X_HuH;3` Superior Performance: Provides excellent water uptake and rapid swelling . /MediaBox [0 0 612 792] : 160182 Date Approved: 05/25/2010 Revision No. <> No. Our customers around the world enjoy the benefits of TEXTURECEL NaCMC in various wound care products, too. At the same time, its pronounced shear-thinning behavior enables handling of even highly viscous solutions. Avicel CL-611 Microcrystalline Cellulose and Sodium Microcrystalline cellulose (MCC) is the most commonly used spheronizing aid in a formulation undergoing extrusion spheronization.
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